泌尿生殖道支原体感染1045例临床资料及药敏分析

Analysis of 1045 Patients with Genitourinary Tract Mycoplasma Infection and Drug Susceptibility

目的为了解泌尿生殖道解脲脲原体(UU)和人型支原体(MH)的感染情况及其对抗生素的敏感性,以指导临床用药。方法应用支原体培养、鉴定、药敏试剂盒,对3602例可疑泌尿生殖道感染患者的泌尿生殖道标本进行UU和MH的检测,并测定其对9种常用抗生素的敏感性。结果检出1045例支原体阳性者,检出率为29.01%,其中UU,MH,UU+MH检出率分别为23.96%,0.58%及4.47%;UU对米诺环素最敏感,其次为多西环素和克拉霉素。结论支原体引起的泌尿生殖道感染以UU感染为主;结合支原体药敏结果合理选择抗生素则更高效。

Objective In order to guide the clinical medication,We detected ureaplasma urealyticum (UU) and mycoplasma hominis (MH) in patients with urogenital infection and then analysed their sensitivity to antibiotics.Methods Using mycoplasma culture,identification and sensitivity testing reagent box,3602 doubtful patients with mycoplasma infection were detected for UU,MH and their sensitivity to 9 antibiotics.Results 1045 cases were mycoplasma positive and its positive rate was 29.01%.The positive rates of UU、MH and UU with MH were respectively 23.96%,0.58% and 4.47%.The result of sensitivity showed that UU was the most sensitive germ to Minocycline,and more sensitive to Doxycycline and Klarithromycin.Conclusions The genitourinary infection caused by MH that is especially UU infection.It is the best method that reasonable adoption of antibiotics according to the results of susceptibility test.