用熊去氧胆酸治疗肝脏疾病的疗效观察

ursodeoxycholic acid for the treatment of liver diseases to oxygen analysis

目的:探讨用熊去氧胆酸治疗肝脏疾病的临床效果。方法:对2012年1月~2013年1月期间在我院住院治疗的40例肝脏疾病患者的临床资料进行回顾性研究。我们将这40例患者随机分为实验组和对照组,其中对照组有16例患者,治疗组有24例患者。我们给对照组患者使用胆维他进行治疗,给实验组患者使用熊去氧胆酸进行治疗。两组患者的治疗时间均为六周。治疗结束后,比较两组患者纳少、腹胀、乏力、黄疸和肝肿大症状的缓解情况。结果:在治疗前,两组患者中存在纳少、腹胀、乏力、黄疸和肝肿大症状人数的比例相比无显著性差异。治疗结束后,实验组患者中没有人出现纳少、腹胀、乏力和黄疸的症状,仅有1人出现肝肿大的症状。对照组患者中出现纳少、腹胀、乏力、黄疸和肝肿大症状的人数分别为4例、4例、4例、6例和5例。实验组患者纳少、腹胀、乏力、黄疸和肝肿大症状的缓解情况明显优于对照组患者,二者相比差异具有显著性(P【0.05)。结论:用熊去氧胆酸治疗肝脏疾病疗效显著,可有效地缓解患者出现的纳少、腹胀、乏力、黄疸和肝肿大症状,改善其肝功能。此药值得在临床上推广使用。

objective : To study the oxygen analysis to ursodeoxycholic acid in the treatment of liver diseases. Methods :Stay in the hospital treatment of 40 patients with liver disease were randomly divided into experimental group and control group, control group patients take bravery dimension treatment, he has to take six weeks, the experimental group patients taking ursodeoxycholic acid treatment, the total take six weeks. All patients did not use other steroid preparations. Results :experimental group in the small, abdominal distension, fatigue, jaundice, and liver enlargement symptoms of slow were superior to control group, especially the more significant the jaundice. Conclusion : ursodeoxycholic acid in liver disease treatment have good curative effect, can significantly improve liver function in patients with liver disease. Is worth further promotion and application in the clinical practice.