Stimuli-responsive nano-reserveriors drug delivery systems based on inorganic nanoparticles

The convergence of nanotechnology,material science,biology and medicine promotes the rapid development of nano-biomedicine,which plays an important role in relieving the pain of patients and improving the health of human,in particular of cancer therapy.Construction of stimuli-responsive controlled release system for targeted drug delivery to specific cells is essentially important for cancer therapy since most chemotherapeutics are severely toxic[1].During past decades,magnetic nanoparticles（MNPs）and mesoporous silica nanoparticles（MSNs）attracted much attention in the related field,due to their good biocompatibility。

The convergence of nanotechnology,material science,biology and medicine promotes the rapid development of nano-biomedicine,which plays an important role in relieving the pain of patients and improving the health of human,in particular of cancer therapy.Construction of stimuli-responsive controlled release system for targeted drug delivery to specific cells is essentially important for cancer therapy since most chemotherapeutics are severely toxic[1].During past decades,magnetic nanoparticles（MNPs）and mesoporous silica nanoparticles（MSNs）attracted much attention in the related field,due to their good biocompatibility,large