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促血小板生成素治疗慢性肾衰竭血小板减少临床研究 被引量:1

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摘要 目的探讨促血小板生成素(TPO)治疗,慢性肾衰竭患者血小板减少的临床疗效和慢性肾衰竭患者TPO水平、TPO与肾功能及血小板的关系。方法将健康人作为对照组,慢性肾衰竭血小板减少患者作为实验组,应用酶标仪测定健康对照组和实验组TPO水平,同时应用血细胞测定仪和全自动生化测定仪检测慢性肾衰竭患者血常规、肾功能和肝功能等。结果慢性肾衰竭患者较正常对照组血清TPO降低(P0.05),慢性肾衰竭患者应用TPO治疗后两周内,血小板明显上升(P<0.01),慢性肾衰竭患者TPO水平与血小板呈正相关,TPO水平与血尿素氮、肌酐呈负相关。结论 TPO治疗慢性肾衰竭血小板减少具有好的疗效,未发现明显副作用。
机构地区 吉大一院肾病科
出处 《环球中医药》 CAS 2013年第S1期80-81,共2页 Global Traditional Chinese Medicine
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