中西医结合治疗甲状腺机能亢进症(附57例临床观察)

Clinical Observation on Hyperthyroidism Complex Treated with TCM and Western Medicine

目的 观察中药复方平亢方、他巴唑联合治疗甲状腺机能亢进症 (简称甲亢 )的临床疗效。方法 5 7例患者随机分为 2组 ,治疗组 (31例 )予以平亢方、他巴唑治疗 ;对照组 (2 6例 )予以他巴唑治疗。 3个月为1个疗程 ,均观察 2个疗程。观察 2组治疗前后甲亢的临床症状、体征、甲状腺激素水平的改善情况的差异。结果 治疗组和对照组总三碘甲状腺原氨酸 (T3)、总甲状腺素 (T4 )、游离三碘甲状腺原氨酸 (FT3)、游离甲状腺素 (FT4 )的水平均有降低 ,TSH明显上升 (P <0 0 5 )。治疗组多项指标降低优于对照组 (P <0 0 5 ) ;治疗组总有效率 (96 77% ) ,显著高于对照组 (84 73% ,P <0 0 5 ) ;而且治疗组患者临床症状和体征改善也优于对照组 ,尤其是降低甲亢指数积分明显优于对照组 (P <0 0 5 )。结论 平亢方与他巴唑治疗甲亢疗效肯定 ,其作用机制可能与抑制能量代谢 ,抑制甲状腺激素的分泌 。

Objective To observe curative effect of Pingkangfang and methimazolum treating hyperthyroidism. Methods 57 cases of such patient were divided into two groups. Group I was given Pingkangfang and methimazolum and control group was given methimazolum 3 month was a course for 2 courses observation. The improvement of clinical symptom, signs and thyroid hormone level were observed. Results T 3, T 4, FT 3 and FT 4 in therapy group were decreased and TSH was increases significantly that those in control group (P<0.05). The clinical symptom and signs in therapy group were improved better than those in control group with total effective rate of 96.77% in therapy group and 84.73% in control group. Conclusion Pingkangfang could treat the hyperthyroidism effectively with mechanism of inhibit energy metabolism, secretion of thyroid and block the absorption of thyroid hormone.