期刊文献+

重型颅脑损伤合并脑疝及弥散性血管内凝血的诊治分析 被引量:3

Severe traumatic brain injury combined with cerebral hernia and disseminated intravascular coagulation: diagnosis and treatment
下载PDF
导出
摘要 目的总结颅脑损伤合并脑疝及弥散性血管内凝血(disseminated intravascular coagulation,DIC)患者的诊治经验,为临床实践提供参考。方法收集本院2013年3月至2014年3月期间重型颅脑损伤101例患者,其中出现脑疝及DIC的病例共9例,回顾分析诊治经过。结果本组9例重型颅脑损伤合并脑疝及DIC,经手术后治愈0例,好转1例,植物生存2例,死亡6例,死亡率约66.7%。结论重型颅脑损伤患者合并脑疝及DIC死亡率极高,在围手术期更快纠正DIC、更安全有效进行手术治疗,配合术后亚低温治疗,以降低患者的死亡率。 Objective To summarize the experience in treating patients with severe traumatic brain injury combined with cerebral hernia and disseminated intravascular coagulation (dic).Method in 101 cases of severe traumatic brain injury from may 2013 to may 2014, 9 cases with cerebral hernia and dic were selected, which were retrospectively analysed and summarized.Resultnone of the 9 cases was cured, among which the condition of 1 patient improved;2 patients presented plant survival status, while 6 patients died after operation and the mortality was about 66.7%.Conclusion The death rate in patients with severe traumatic brain injury combined with cerebral hernia and dic is obviously high.it is proved that correcting dic with faster speed perioperatively,and operating more safely and effectively cooperated with postoperative hypothermia treatment may be beneficial to reduce the patient's mortality.
出处 《创伤与急诊电子杂志》 2014年第1期21-23,共3页 Journal of Trauma and Emergency(Electronic Version)
关键词 重型颅脑损伤 脑疝 弥散性血管内凝血 Severe traumatic brain injury Cerebral hernia Disseminated intravascular coagulation
  • 相关文献

参考文献7

二级参考文献105

  • 1詹前美.D-二聚体、FDP检测的临床意义[J].中国厂矿医学,2006,19(4):362-362. 被引量:15
  • 2Brohi K, Cohen M J, Ganter MT, et al. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis [ J]. J Trauma,2008,64(5 ) : 1211-1217.
  • 3Brohi K, Singh J, Heron M, et al. Acute traumatic coagulopathy [ J ]. J Trauma,2003,54 ( 6 ) : 1127-1130.
  • 4Niles SE, McLaughlin DF, Perkins JG, et al. Increased mortality associated with the early coagulopathy of trauma in combat casualties [ J]. J Trauma,2008,64(6) : 1459-1463.
  • 5Maegele M, Lefering R, Yucel N ,et al. Early coagulopathy in multiple injury : an analysis from the German trauma registry an 8724 patients [ J ]. Injury,2007,38 ( 3 ) :298-304.
  • 6Hrafnkelsdottir T, Erlinge D, Jern S. Extracellular nucleotides ATP and UTP induce a marked acute release of tissue-type plasminogen activator in vivo in man [ J ]. Thromb Haemost, 2001,85 ( 1 ) : 875-881.
  • 7Brohi K,Cohen M J, Ganter MT,et al. Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway.'? [ J]. Ann Surg,2007,245 (5) :812-818.
  • 8Rezaie AR. Vitronectin functions as a cofactor for rapid inhibition of activated protein C by plasminogen activator inhibitor-1. Implications for the mechanism of profibrinolytic action of activated protein C [ J ]. J Biol Chem,2001,276 (19) : 15567-15570.
  • 9Bajzar L, Jain N, Wang P, et al. Thrombin activatable fibrinolysis inhibitor:not just an inhibitor of fibrinolysis [ J ]. Cfit Care Med, 2004,32( Suppl 1 ) :320-324.
  • 10Coats TJ, Brazil E, Heron M, et al. Impairment of coagulation by commonly used resuscitation fluids in human volunteers[ J ]. Emerg Med J,2006,23 ( 11 ) :846-849.

共引文献108

同被引文献13

引证文献3

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部