丁苯酞联合血栓通治疗缺血性脑卒中患者神经功能的效果

Effects of NBP combined with Xueshuantong on the improvement of neural function in patients with ischemic cerebral stroke

目的研究丁苯酞联合血栓通治疗对改善缺血性脑卒中患者神经功能的效果。方法选取缺血性脑卒中患者105例,随机分为中药血栓通治疗组(A组)、西药丁苯酞治疗组(B组)和丁苯酞联合血栓通结合治疗组(C组)各35例。A组采用血栓通注射剂,并加入5%的葡萄糖,每天2次静脉滴注;B组采用丁苯酞软胶囊、阿司匹林肠溶片以及三磷酸腺苷片3种西药;C组采用A组血栓通和B组丁苯酞结合治疗患者。脑卒中残损评价表(CSS)作为神经功能恢复状况的评价标准。结果 3组间CSS评分在各时间点差异无统计学意义;3组CSS评分较入组前明显降低,P<0.05,有统计学意义。3组疗效中C组最优,总有效率为57.14%。结论丁苯酞联合血栓通治疗缺血性脑卒中对患者神经功能恢复比较单独运用中药血栓通或西药丁苯酞效果更佳,值得进一步推广。

Objective To study effects of NBP combined with Xueshuantong on the improvement of neural function in patients with ischemic cerebral stroke. Methods One hundred and five cases ischemic cerebral stroke patients were selected,randomly divided into 3 groups: Xueshuantong treatment group( Group A),NBP treatment group( Group B) and integrative medicine treatment group( Group C). Group A adopted Xueshuantong injecta which mixed with 5% glucose,twice each day,intravrnous injection. Group B adopted butylphthalide soft capsule,enteric aspirin tablets and ATP tablets. Group C combined the methods of Group A and Group B. The China stroke scale( CSS) was taken as the evaluation criteria of neurological functions recovery. Results In all the three groups,the CSS scores had no difference at each time point( P > 0. 05). Compared with the score before the treatment,the score in all three groups declined obviously( P < 0. 05). The best effect was shown in Group C,with the total effective rate of 57. 14%.Conclusion Integrative medicine protocols had better effects on neurological function recovery compared with traditional Chinese medicine Xueshuantong or western medicine NBP alone.