期刊文献+

博尔纳病病毒感染致病机制的研究进展

原文传递
导出
摘要 博尔纳病病毒是一种新发神经系统感染病毒,一种非细胞溶解的、单股负链的RNA病毒,是单股负链RNA病毒目博尔纳病毒科的典型代表,有严格的嗜神经性,呈低产量、非溶细胞性复制.感染范围从马、牛,羊、鸟、灵长类等剑人类,造成博尔纳病(Borna disease,BD),一种致死性中枢神经疾病,临床上以精神、行为异常为主要表现.自然感染以马和羊为主,人类的BDV感染可能与部分神经精神疾病的发病有关.其致病机制尚不清楚,给博尔纳病的流行病学调查和诊断、治疗带来很大的影响,现就博尔纳病病毒感染机制综述如下.
作者 姚能云 徐平
出处 《国际病毒学杂志》 2008年第6期-,共5页 International Journal of Virology
基金 贵州省科学技术基金,贵州省省长基金
  • 相关文献

参考文献3

二级参考文献60

  • 1Mayo MA,Pringle CR.Virus Taxonomy-1997.J Gen Virol,1998,79:649-657.
  • 2Staeheli P,Sauder C,Hausmann J,et al.Epidemiology of Borna disease virus.J Gen Virol,2000,81(Pt 9):2123-2135.
  • 3Pletnikov MV,Rubin SA,Moran TH,et al.Exploring the cerebellum with a new tool:neonatal Borna disease virus (BDV)infection of the rat's brain.Cerebellum,2003,2:62-70.
  • 4Hans A,Bajramovic JJ,Syan S,et al.Persistent,non-cytolytic infection of neurons with Borna disease virus interferes with ERK 1/2signaling and abrogates BDNF-induced synaptogenesis.FASEB J,2004,18:863-865.
  • 5Gonzalez-Dunia D,Watanabe M,Syan S,et al.Synaptic pathology in Borna disease virus persistent infection.Virol,2000,74:3441-3448.
  • 6Mattson MP,Maudsley S,Martin B.BDNF and 5-HT:a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders.Trends Neurosci,2004,27(10):589-594.
  • 7McAllister AK,Katz LC,Lo DC,Neurotrophins and synaptic plasticity.Annu Rev Neurosci,1999,22:295-318.
  • 8Dietz D,Vogel M,Rubin S,et al.Developmental alterations in serotoninergic neurotransmission in Borna disease virus (BDV)infected rats:a multidisciplinary analysis.Neurovirol,2004,10:267-277.
  • 9Kamitani W,Ono E,Yoshino S,et al.Glial expression of Boma disease virus phosphoprotein induces behavioral and neurological abnormalities in transgenic mice.Proc Natl Acad Sci USA,2003,100:8969-8974.
  • 10Nakamura Y,Nakaya T,Hagiwara K,et al.High susceptibility of Mongolian gerbil (Meriones ungulculatus) to Borna disease virus.Vaccine,1999,17:480-489.

共引文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部