细胞信号转导与肿瘤多药耐药性基因
摘要
多药耐药性基因过表达是肿瘤产生多药耐药现象的重要原因,其表达的调控受多种因素控制.本文就几种细胞信号转导机制在其表达调控中的作用做一综述.
出处
《国际耳鼻咽喉头颈外科杂志》
2008年第1期-,共3页
International Journal of Otolaryngology-Head and Neck Surgery
参考文献2
-
1袁亚维,孙爱民,李传刚.KBV200细胞多药耐药与蛋白激酶C表达上调的关系(英文)[J].第一军医大学学报,2005,25(11):1341-1343. 被引量：2
-
2BoChen,FengJin,PingLu,Xiang-LanLu,Ping-PingWang,Yun-PengLiu,FanYao,Shu-BaoWang.Effect of mitogen-activated protein kinase signal transduction pathway on multidrug resistance induced by vincristine in gastric cancer cell line MGC803[J].World Journal of Gastroenterology,2004,10(6):795-799. 被引量：22
二级参考文献13
-
1Edgar Staren,Takeshi Iwamura,Hubert Appert,John Howard.Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2[J].World Journal of Gastroenterology,2001,7(1):143-148. 被引量：12
-
2张晓红,张福荣,籍秀娟,李占荣.KB细胞耐药株的建立及其耐药机制的探讨[J].药学学报,1994,29(4):246-251. 被引量：63
-
3Karp JE. MDR modulation in acute myelogenous leukemia: is it dead[ J ] ? Leukemia, 2001, 15(4): 666-7.
-
4Blobe GC, Sachs CW, Khan WA, et al. Slective regulation of protein kinase C isoenzymes in multidrug-resistant MCF-7 cells [J]. J Biol Chem, 1993, 268(1): 658-64.
-
5Gravitt KR, Ward NE, Fan D, et al. Evidence that protein kinase C-activation is a critical event in phorbol esters induced multiple drug resistance in human colon cancer cells [J]. Biochem Pharmacol, 1994, 48 (2): 375-81.
-
6Schwartz GK, Arkin H, Holland JF, et al. Protein kinase Cactivity and multidrug resistance in MOLT-3 human lymphoblastic leukemia cell resistant to trimetrexate [J ]. Cancer Res, 1991, 51 (1):55-61.
-
7Gill PK, Gescher A, Gant TW. Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta[J]. Eur J Biochem, 2001,268 (15): 4151-7.
-
8Masanek U, Stammler G, Volm M. Modulation of multidrug resistance in human ovarian cancer cell lines by inhibition of P-glycoprotein 170 and PKC isoenzymes with antisense oligonucleotides [J]. J Exp Ther Oncol, 2002, 2(1): 37-41.
-
9ZHANG Li Jian 1, CHEN Ke Neng 1, XU Guang Wei 1, XING Hai Ping 2 and SHI Xiao Tian 2.Congenital expression of mdr-1 gene in tissues of carcinoma and its relation with patho morphology and prognosis[J].World Journal of Gastroenterology,1999,5(1):58-61. 被引量：15
-
10韩英,时永全,李玲,樊代明.蛋白激酶C同工酶PKC-α及PKC-βⅠ在胃癌及其耐药细胞中的表达和功能[J].中华肿瘤杂志,2001,23(2):103-106. 被引量：26
共引文献22
-
1刘艳,张金山,张立会,权海燕.非酒精性脂肪性肝病、酒精性肝病与胰岛素抵抗的关系[J].中国老年学杂志,2024,44(10):2555-2559.
-
2王华.酒精相关性肝病[J].科学通报,2023,68(20):2606-2618.
-
3冯雪,郑建华.卵巢癌化疗耐药相关细胞信号转导通路的研究进展[J].妇产与遗传（电子版）,2012,2(1):35-38. 被引量：3
-
4沈松杰,郭俊超,廖泉,赵玉沛.MAPK信号转导通路在肿瘤化疗耐药中的作用[J].国外医学（肿瘤学分册）,2005,32(8):579-582. 被引量：9
-
5杜舟,余震.耐药基因在胃癌化疗中的研究进展[J].浙江临床医学,2006,8(4):439-440. 被引量：4
-
6郭俊超,赵玉沛,廖泉,陈革,朱预.丝裂原活化蛋白激酶磷酸酶1与胰腺癌细胞获得性耐药的关系[J].中华外科杂志,2006,44(7):473-475. 被引量：3
-
7庞林荣,丁克峰.肿瘤多药耐药与细胞信号转导的研究进展[J].国际外科学杂志,2007,34(10):696-699. 被引量：2
-
8闫峰,王效民.MAPK信号转导通路与肝癌细胞多药耐药[J].陕西医学杂志,2007,36(10):1400-1402. 被引量：1
-
9谢德荣,郭双双,杨琼,江志敏,陈邓林,毕卓菲,马雯.ERK通路在胰腺癌细胞株SW1990吉西他滨化疗耐药中的作用[J].中国肿瘤临床,2008,35(14):829-832. 被引量：2
-
10赵越,林蓓,郝莹莹,严丽梅,刘娟娟,朱连成,张淑兰.卵巢癌细胞系RMG-Ⅰ Lewis(y)抗原含量变化对其卡铂耐药性的影响[J].生物化学与生物物理进展,2008,35(10):1175-1182. 被引量：10
-
1王生才,房居高.PIK3CA基因与头颈部鳞状细胞癌[J].国际耳鼻咽喉头颈外科杂志,2009,33(2):104-107.
-
2王征旭,何振平,吴祖泽,李元敏,张维维.Effects of adenoviral vector-mediated transduction of human p53,B7-1 and GM-CSF genes on liver cancer cells[J].Journal of Medical Colleges of PLA(China),1999,14(4):247-257. 被引量：1
-
3王传泰,钱军.黏着斑激酶与结直肠癌的关系[J].中华全科医学,2010,8(3):362-363. 被引量：1
-
4施扬,张秋娟.垂体腺瘤发病机制研究进展[J].医药前沿,2016,0(18):16-18. 被引量：1
-
5蔡成福,任刚,赵德安.Wnt信号传导通路与鼻咽癌的关系[J].国际耳鼻咽喉头颈外科杂志,2012,36(1):19-23. 被引量：1
-
6赵燕秋,肖冰,陈宝军,乔泰东,樊代明.Upregulation of drug sensitivity of multidrug resistant SGC7901/VCR human gastric cancer cells by bax gene transduction[J].Chinese Medical Journal,2000(11):17-20. 被引量：10
-
7邓洁英,史轶蘩,尹娟娟.Some changes of receptor and postreceptor signal transduction regulated by somatostatin in pituitary hGH-secreting adenomas[J].Chinese Medical Journal,1997(9):22-25.
-
8宋波,金锡御,潘进洪,方强,杨航.以体外侵袭力构建高转移膀胱癌细胞亚系[J].中华泌尿外科杂志,1998,19(7):387-390. 被引量：3
-
9张永亮,陈修煦,来茂德.化疗药物诱导的肿瘤细胞凋亡和相关因子的调控[J].国外医学（遗传学分册）,2002,25(3):121-126. 被引量：7
-
10沈永泉,崔莲仙,何维,薛莉,巴德年.ANTITUMOR EFFECTS OF HUMAN IL-15 GENE MODIFIED LUNG CANCER CELL LINE[J].Chinese Journal of Cancer Research,1997,9(4):8-12. 被引量：2
