拉曼光谱技术在肿瘤研究中的进展

Raman spectrum technology in tumor research application

蛋白质、脂类、碳水化合物和核酸是构成正常细胞和组织的主要物质,在恶变早期过程中,这些化学物质的结构、构象和数量都发生了明显的改变,但临床症状和医学影像学尚无明显的变化.而拉曼光谱却能反映早期变化,因此拉曼光谱技术有望成为恶性肿瘤早期诊断及癌变机制研究的重要手段.就目前拉曼光谱技术在肿瘤研究中的应用以及最新进展作一综述.

The protein,the fats,the carbohydrate and the nucleic acid are the main constituent material of normal cell and organizations. In the early process of becoming malignant,these chemical substance's structure,the conformation and quantity has had the obvious change,but this time clinical symptoms and medicine phantom study still has not obvious change.But the Raman spectrum can actually reflect these changes.Therefore the Raman spectrum technology becomes important means of the malignant tumor early diagnosis and the cancer mechanism research hopefully.This article makes a summary on the present as well as the progress reviewed of Raman spectrum technology in the tumor research application.