正常孕妇早期妊娠子宫动脉血流图参数初步研究

Analysis on Related Parameter of Uterine Artery Blood Flow in the First Trimester of Normal Pregnancy

目的 运用彩色多普勒超声经腹部检测早期妊娠子宫动脉血流图血流参数和频谱特征,建立11~14孕周双侧子宫动脉血流参数,搏动指数(PI)的正常值范围。方法 2013年10月1日至2014年7月1日于吉林大学第二临床医院建档行产前检查的孕妇共207例,通过彩色多普勒超声在孕11~14周检测子宫动脉血流PI值,记录舒张早期切迹。结果 111~14孕周子宫动脉血流PI值呈正态分布,PI值正常参考值范围(95%的界限)PI(1.48±1.10)。2在11~14孕周,78.7%的孕妇存在子宫动脉切迹,其中双侧子宫动脉切迹约54.6%,单侧子宫动脉切迹24.1%。3双侧子宫动脉手动描迹和机测获得的PI值有统计学差异(P【0.05)。结论 早期妊娠子宫动脉血流PI值随着妊娠天数的增加逐渐降低。本研究建立经腹超声11~14孕周血流PI值参考值区间并记录舒张早期切迹特征,有助于进一步研究早期妊娠异常子宫动脉血流图与妊娠期高血压疾病、胎儿宫内生长受限等不良妊娠结局的相关性。

Objective To detect related parameters of uterine artery blood flow and characteristics of Doppler in the first trimester of pregnancy,and to establish normal reference value range of bilateral uter-ine artery pulsatility index (PI).Method From October1 ,2013 to July1 ,2014,a total of 207pregnancies, refered to our institution for routine prenatal examination,were included in this cohort study.The left and right uterine arteries were examined by color and pulsed Doppler and the mean pulse index (PI)as well as the presence of a bilateral parly diastolic notch were recorded.Results ① Mean uterine artery PI in first tri-mester of pregnancy showed a normal distribution,the reference value range of PI is PI(1.48±1.10);② In the first trimester of pregnant,78.7% of pregnant women have uterine artery notch,54.6% is bilateral,24.1% is single;③ The difference between the manual measurement of uterine artery and mechanical measurement has statistically significance (P<0.05).Conclusions Mean uterine artery PI in the first trimester of pregnancy shows a significant linear decrease.To establish the normal reference value range of PI and the characteris-tics of early diastolic notch is helpful to further study the relevance between abnormal uterine artery blood flow and hypertensive disorders complicating pregnancy,FGR and poor pregnancy finale.