长效伊维菌素注射液治疗家兔螨虫病对比试验

The Comparison Studies on the Curative Effect of the Long-acting Ivermectin Injection Treating Mites Infection in Rabbit

本试验进行了长效伊维菌素注射液(第1组)与常规伊维菌素注射液(第2组)治疗兔螨虫的疗效比较。结果表明:两种伊维菌素注射液用药后前7天的临床效果基本一致;但7天以后,第2组兔有轻微的瘙痒症状,有些兔皮肤出现丘斑;到45天时,部分兔出现明显的病灶。而第1组用药后14天,患部长出新毛,至试验结束时,患兔痊愈。用药7天后,第1组活疥螨虫减少率为91.2%,第2组活疥螨虫减少率为75.8%,显著低于第1组(P<0.05);第1组活痒螨的减少率为90.4%,而第2组为74.5%,显著低于第1组(P<0.05)。用药后第14～45天,第1组无疥螨和痒螨感染,而第2组活疥螨和活痒螨数量开始逐渐增加,出现重复感染。

The studies were compared the efficacy of treatment of rabbit mites between long-acting ivermectin injection(group1) and conventional ivermectin injection(group2). The results show that: the clinical effects of this two ivermectin injection was basically the same within 7 days after treatment.But the seven days later,the group 2 of rabbits had slight pruritus symptoms, some rabbits had skin papules. At 45 days, some rabbits had obvious lesions. The affected area of group 1 rabbits grow new hair. At end of the experiment, suffering from rabbit healed. All patients of rabbits were cured. The 7 days after treatment, the live scabies mites of group 1 was reduced by 91.2%, but group 2 was reduced by 75.8%, it was significantly lower than the group1(P<0.05); The live itch mites of group1 was reduced by 90.4%, but group2 was reduced by 74.5%, it was significantly lower than the group 1(P <0.05). The 14 to 45 days after treatment, the group 1 have not infected the scabies mites and itch mites, but the live scabies mites and itch mites of group 2 began to increase, and appeared super infection.