The relationship between the hepatitis B virus base core and precore/core promoter mutations and the development of cirrhotic hepatocellular carcinoma and noncirrhotic hepatocellular carcinoma
The relationship between the hepatitis B virus base core and precore/core promoter mutations and the development of cirrhotic hepatocellular carcinoma and noncirrhotic hepatocellular carcinoma
摘要
Objective To investigate the mutations of basal core promoter(BCP) and precore(PreC) region of hepatitis B virus(HBV) and the association with the development of hepatocellular carcinoma in patients with chronic HBV infection. Methods Totally 381 untreated HBV patients were recruited from the Department of
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