The proteasome inhibitor MG132 attenuates skeletal muscle atrophy in a rat model of chronic obstructive pulmonary disease
The proteasome inhibitor MG132 attenuates skeletal muscle atrophy in a rat model of chronic obstructive pulmonary disease
摘要
Objective To investigate the effect of the proteasome inhibitor MG-132 on skeletal muscle atrophy in a rat model of chronic obstructive pulmonary disease (COPD) and is potential mechanisms.Methods The COPD rat model was established by instillation of LPS and
-
1舒家泽.Nose-only cigarette smoke exposure plus airway lipopolysaccharide inhalation induced chronic obstructive pulmonary disease and associated pulmonary hypertension in mice[J].China Medical Abstracts(Internal Medicine),2016,33(1).
-
2Interstitial lung disease[J].China Medical Abstracts(Internal Medicine),2010,0(3):164-166.
-
3张劲农,郑灵,白明.Dynamic Expression of Tumor Necrosis Factor-α and Vascular Endothelial Growth Factor in Rat Model of Pulmonary Emphysema Induced by Smoke Exposure[J].Journal of Huazhong University of Science and Technology(Medical Sciences),2007,27(5):505-507. 被引量：1
-
4RESPIRATORY SYSTEM[J].China Medical Abstracts(Internal Medicine),2001,18(3):140-147.
-
5ENDOCRINOLOGY[J].China Medical Abstracts(Internal Medicine),2000,17(2):80-86.
-
6Diabetes mellitus[J].China Medical Abstracts(Internal Medicine),2007,24(4):195-197.
-
7Xiao-Hong Lü1,Bing-Yin Shi2,Lan He1,Huai-Yu Wang3,Ming He1,Wei Li11.Department of Rheumatology,2.Department of Endocrinology,3.Department of Hematology,the First Affiliated Hospital,Medical School of Xi’an Jiaotong University,Xi’an 710061,China.Increased expression of the 20S proteasome in peripheral blood mononuclear cells of type 2 diabetic patients[J].Journal of Pharmaceutical Analysis,2010,22(4):255-259.
-
8陈新敬,浦晓东.泛素及大鼠蛋白酶体第三亚基在大鼠颈总动脉球囊损伤后的表达[J].中华心血管病杂志,2008,36(10):931-935.
-
9范鋆钰,孙凌云.吸烟与原发性胆汁性肝硬化发病风险相关性的Meta分析[J].临床肝胆病杂志,2015,31(10):1625-1629.
-
10DISEASE CAUSED BY CHEMICAL AND PHYSICAL AGENTS[J].China Medical Abstracts(Internal Medicine),1996,13(1):6-7.
