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Systematic review of absorbable vs non-absorbable sutures used for the closure of surgical incisions

Systematic review of absorbable vs non-absorbable sutures used for the closure of surgical incisions
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摘要 AIM: To report a systematic review of published randomized controlled trials(RCTs) investigating the role of absorbable suture(AS) against non-AS(NAS) used for the closure of surgical incisions.METHODS: RCTs investigating the use of AS vs NAS for the closure of surgical incisions were statistically analysed based upon the principles of meta-analysis and the summated outcomes were represented as OR.RESULTS: The systematic search of medical literature yielded 10 RCTs on 1354 patients. Prevalence of wound infection(OR = 0.97; 95%CI: 0.56, 1.69; Z = 0.11; P = 0.92) and operative morbidity(P = 0.45) was comparable in both groups. Nonetheless, the use of AS lead to lower risk of wound break-down(OR = 0.12; 95%CI: 0.04, 0.39; Z = 3.52; P < 0.0004).CONCLUSION: This meta-analysis of 10 RCTs demonstrates that the use of AS is similar to NAS for skin closure for surgical site infection and other operative morbidities. AS do not increase the risk of skin wound dehiscence,rather lead to a reduced risk of wound dehiscence compared to NAS. AIM: To report a systematic review of published randomized controlled trials(RCTs) investigating the role of absorbable suture(AS) against non-AS(NAS) used for the closure of surgical incisions.METHODS: RCTs investigating the use of AS vs NAS for the closure of surgical incisions were statistically analysed based upon the principles of meta-analysis and the summated outcomes were represented as OR.RESULTS: The systematic search of medical literature yielded 10 RCTs on 1354 patients. Prevalence of wound infection(OR = 0.97; 95%CI: 0.56, 1.69; Z = 0.11; P = 0.92) and operative morbidity(P = 0.45) was comparable in both groups. Nonetheless, the use of AS lead to lower risk of wound break-down(OR = 0.12; 95%CI: 0.04, 0.39; Z = 3.52; P &lt; 0.0004).CONCLUSION: This meta-analysis of 10 RCTs demonstrates that the use of AS is similar to NAS for skin closure for surgical site infection and other operative morbidities. AS do not increase the risk of skin wound dehiscence,rather lead to a reduced risk of wound dehiscence compared to NAS.
作者 Muhammad S Sajid Malcolm R Mc Fall Pauline A Whitehouse Parv S Sains
机构地区 Western Sussex Hospitals NHS Trust Department of General
出处 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2014年第12期241-247,共7页 世界胃肠外科杂志（英文版）（电子版）
关键词 CLOSURE analysed SUTURE wound OPERATIVE comparable statistically MORBIDITY INCLUSION heterogeneity Skin closure Surgical site infection Wound dehiscence Absorbable sutures Non-absorbable suture
分类号 R615 [医药卫生—外科学]
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参考文献4

  • 1Norifumi Harimoto,Ken Shirabe,Tomoyuki Abe,Takafumi Yukaya,Eiji Tsujita,Tomonobu Gion,Kiyoshi Kajiyama,Takashi Nagaie.Prospective randomized controlled trial investigating the type of sutures used during hepatectomy[J].World Journal of Gastroenterology,2011,17(18):2338-2342. 被引量：11
  • 2Dirk Richter,Alexander Stoff,Venkat Ramakrishnan,Klaus Exner,Jan Jernbeck,Phillip N. Blondeel.A Comparison of a New Skin Closure Device and Intradermal Sutures in the Closure of Full-Thickness Surgical Incisions[J].Plastic and Reconstructive Surgery.2012(4)
  • 3Gleeson Rebello,Ravi Parikh,Brian Grottkau.Coaptive Film Versus Subcuticular Suture: Comparing Skin Closure Time Following Identical, Single-session, Bilateral Limb Surgery in Children[J].Journal of Pediatric Orthopaedics.2009(6)
  • 4Peng Chiong Tan,Sarah Mubarak,Siti Zawiah Omar.Absorbable versus nonabsorbable sutures for subcuticular skin closure of a transverse suprapubic incision[J].International Journal of Gynecology and Obstetrics.2008(2)

二级参考文献20

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共引文献10

World Journal of Gastrointestinal Surgery
2014年 第12期

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