经尿道膀胱肿瘤电切术治疗高龄膀胱癌合并反复性出血的应用体会

Clinical effect of transurethral resection of bladder tumor for elderly patient with recurrent bleeding

目的：：评价经尿道膀胱肿瘤电切术(transurethral resection of bladder tumor,TURBT)在治疗高龄膀胱癌合并反复性出血中的疗效及安全性.方法：2003年5月~2013年5月共收治高龄膀胱癌合并反复性出血患者62例,行TURBT治疗.结果：62例患者手术均顺利完成,无术中死亡,无术中输血；术后常规用丝裂霉素40 mg＋0.9％生理盐水40 ml 进行膀胱灌注化疗.术后采用电话随访,随访时间为6~60个月,平均32个月；均能达到良好止血效果,患者生活质量明显改善,5年生存率为79.0％.结论：TURBT处理高龄膀胱癌合并反复性出血止血效果达100％,安全系数高,术后配合丝裂霉素化疗,达到治疗及改善生存质量的目的.

Objective:The aim of this study was to evaluate the efficacy and security of transurethral resection of bladder tumor(TURBT)for bladder carcinoma with recurrent bleeding in elderly patients.Methods:62-patient were selected and treated with TURBT between May 2003 and May 2012,and all people were diagnosed as bladder transitional cell carcinoma by pathology after operation.Results:All people were operated a successful TURBT,without intraoperative blood transfusion or intraoperative death.Conventional postoperatively with mitomycin 40 mg was diluted by 40 mL saline water for bladder perfusion chemotherapy.All people postoperatively information were collected by telephone,and the follow-up time from 6to 60 months,the average time was 32 months.62-patient achieved well hemostasis and significantly improved the quality of the life.Moreover,the 5-year survival rate was arrived79.0% after TURBT.Conclusions:The effect of TURBT treatment of the bladder carcinoma patients with recurrent bleeding reached at 100%,and improved the quality of the life for therapeutic purposes.