联合应用溴隐亭和针灸疗法治疗特发性高催乳素血症合并不孕的疗效观察

clinical observation of Bromocriptine combined Acupuncture and moxibustion of idiopathic hyperprolactine and the infertility

目的:观察联合应用溴隐亭和针灸疗法治疗特发性高催乳素血症合并不孕症的临床疗效。方法:将我院收治的60例特发性高催乳素血症合并不孕症患者根据就诊的次序随机分为对照组和观察组,每组各30例患者。为对照组患者使用溴隐亭进行治疗,为观察组患者在使用溴隐亭的基础上加用针灸疗法进行治疗,对比观察两组患者出现不良反应的情况、性激素水平的变化及妊娠结局。结果:两组患者在进行治疗后其PRL的水平均明显降低,LH、FSH、E、P的水平明显上升,与治疗前相比差异显著(p<0.05),有统计学意义。两组患者在进行治疗后PRL的水平相比较,差异不显著(p>0.05),无统计学意义。两组患者在进行治疗后LH、FSH、E、P的水平相比较差异显著(p<0.001),有统计学意义。观察组患者在进行治疗半年、1年后的妊娠率高于对照组患者,差异显著(p<0.05),有统计学意义。观察组患者出现不良反应的几率低于对照组患者,差异显著(p<0.05),有统计学意义。结论:联合应用溴隐亭和针灸疗法治疗特发高催乳血症合并不孕症有确切的疗效,可显著减轻溴隐亭的副作用,在短期内完全恢复患者的性激素水平,显著改善其排卵功能,提高其妊娠率,此法值得在临床上推广应用。

Objective:To observe the clinical curative effect of the Bromocriptine combined acupuncture and moxibustion of idiopathic hyperprolactine and infertility. Methods: 60 patients in our hospital with idiopathic hyperprolactinemia and infertility patients were randomly divided into two groups according to the order of treatment, control group of 30 patients given bromocriptine 2.5mg / times, twice a day, in the observation group 30 cases of joint control group on the basis of acupuncture treatment, the two groups were observed drug reactions occur, hormone levels change, pregnancy outcome.Results: Both treatments can effectively reduce PRL levels, improve LH, FSH, E, P levels, with the previous treatment was statistically significant difference(p <.0.05), PRL after treatment difference was not statistically significant(p> 0.05), after treatment, LH, FSH, E, P level was statistically significant(p <.0.001); observed number of cases of drug reactions occur group than the control group; observation group and a half after treatment the pregnancy rate was higher. Conclusion: Acupuncture combined bromocriptine treatment of idiopathic infertility high prolactin hyperlipidemia and clear clinical efficacy, adverse drug reaction rate can increase sex hormone levels and pregnancy, worthy of clinical application.