期刊文献+

细胞原癌基因研究进展 被引量:1

原文传递
导出
摘要 原癌基因在正常情况下,不会对细胞产生异常影响。当原癌基因被激活后,基因结构产生突变,基因表达失去控制,最终致使癌变发生。本文将针对常见的原癌基因及其诱发机制作一简要综述。
作者 宋辉 陈宁
出处 《生物技术世界》 2012年第9期4-4,共1页 Biotech World
  • 相关文献

参考文献2

二级参考文献30

  • 1谭敏,宾晓农,陈家堃.痰脱落细胞ras基因突变在肺癌诊断中的意义[J].国际医药卫生导报,2007,13(14):4-7. 被引量:2
  • 2Kovalchuk O, Naumnik W, Serwicka A, et al, K-ras codon 12 mutations may be detected in serum of patients suffering from adeno-and large cell lung carcinoma. A preliminary report[J], Folia Histochem Cytobiol,2001,39(suppl 2) : 70- 72.
  • 3Riely GJ, Kris MG, Rosenbaum D, et ai. Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma[J]. Clin Cancer Res. 2008, 14 (18): 5731-5734.
  • 4Wu CC, Hsu HY, Liu HP, et al. Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications [ J ]. Cancer, 2008, 113 ( 11 ) : 3199- 3208.
  • 5Bachmann M, Kosan C, Xing PX, et al. The oncogenic serine/threonine pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25CD[J]. Int J Biochem Cell Biol,2006,38(3) : 430-443.
  • 6Nasser MW, Datta J, Nuovo G, et al. Down-regulation of micro-RNA-1(miR 1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1[J].J Biol Chem,2008, 283 (48) : 33394-33405.
  • 7Jung JS, Han SGL, Jo UH, et al. Single nucleotide Polymorphisms of Pim-1 in Korean lung cancer patients[J]. J Thorac Oncol,2007,2(8 suppl 4) :487.
  • 8Waenecke-Eberz U, Bollschweiler E, Derbber U. Frequent down-regulation of pim-1 mRNA expression in non-small cell lung cancer is associated with lymph node metastases[J]. Oncol Rep. 2008,20(3): 619- 624.
  • 9Tiseo M, Loprevite M, Ardizzoni A. Epidermal growth factor receptor inhibitors: a new prospective in the treatment of lung cancer[J]. Curr Med Chem Anticancer Agents, 2004, 4 (2): 139-148.
  • 10Galiegue S, Casellas P, Kramar A, et al. Immunohistochemical assessment of the peripheral benzo in breast cancer and its relationship with survival[J]. Clin Cancer Res, 2004, 10 (6) : 2058- 2064.

共引文献1

同被引文献14

引证文献1

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部