彩色多普勒超声检测子痫前期患者胎儿大脑中动脉的价值

A study on the values of color doppler ultrasonography in testing middle cerebral artery of fetuses from pregnant patients with pre-eclampsia

目的研究妊娠期子痫前期患者32~34周胎儿大脑中动脉(MCA)的血流动力学变化规律,探讨其在预测小于孕龄儿的价值。方法对孕32~34周正常胎儿和妊娠期高血压疾病胎儿应用彩色多普勒超声检测大脑中动脉的搏动指数(PI)、阻力指数(RI)、收缩期/舒张期比值(S/D),计算MCA-PI、MCA-RI、MCA-S/D的比值,均取平均值;通过测量BPD、FL、AC、HC等计算胎儿体重,进行相关分析。结果 MCA-PI与MCA-RI、MCA-S/D值在轻度子痫前期(P<0.05)、重度子痫前期(P<0.01)与正常组比较差异有显著性。在轻度子痫前期组与正常组比较差异无显著性(P>0.05)。结论孕妇子痫前期胎儿MCA的血流动力学指标有明显变化,对预测小于孕龄儿具有一定实用价值。

Objective To study the principle of hemodynamic changes of middle cerebral artery(MCA) of fetuses of 32-34 weeks from pregnant patients with pre-eclampsia, and to explore its value in predicting small for gestational age fetuses. Methods Healthy fetuses of 32-34 weeks and fetuses from pregnant patients with pregnancy-induced hypertension were tested via color Doppler ultrasonography to test the pulse index(PI), resistance index(RI) and S/D ratio of MCA, and calculate the average values of MCA-PI, MCA-RI and MCA-S/D ratio; the weights of fetuses were calculated by measuring BPD,FL,HC,AC values, and related analysis was carried out. Results The values of MCA-PI, MCA-RI and MCA-S/D ratio in the group of mild pre-eclampsia(P < 0.05) and the group of severe pre-eclampsia(P < 0.01) was significantly different from that in the healthy group. The values in the group of mild pre-eclampsia were not significantly different from those in the healthy group(P > 0.05). Conclusion The MCA of fetuses from pregnant women with pre-eclampsia shows significant hemodynamic changes, which is worthy of predicting small for gestational age fetuses.