植物表达抗原蛋白及其免疫原性的研究进展

The research progress of plants express antigen protein and immunogenicity

因利用植物生物反应器表达疾病抗原蛋白用于疫苗生产具有安全、廉价和易推广等独特优势,现已成为生物技术领域的研究热点之一。本文对利用植物生物反应器生产口服疫苗的研究进展及存在的弊端如蛋白产量低、口服疫苗易消化降解、免疫耐受等问题进行了综述,并探讨了其潜在的解决办法。

The research about plant as bioreactor for the production of vaccine antigen protein is the hotspots in the field of biotechnology because of it's unique advantages,such as safety,cheap and easy popularization. The present paper reviewed the progress of plant express antigen protein research and some problems like low protein yield,digestion degradation and immune tolerance and proposed some potential solutions for those questions.