摘要
内皮一氧化氮合酶(eNOS)作为调控血管舒张因子NO生成的限速酶,对维持机体NO平衡和适应低氧环境具有重要作用。长期生活在高海拔低氧地区的藏鸡,形成了一套独特的低氧适应机制。作者就eNOS基因结构、编码产物特征和功能进行了综述,并对藏鸡eNOS基因参与低氧适应的遗传机制进行探讨,以期为家禽起源、进化、育种等工作提供借鉴。
As rate-limiting enzyme of regulating Nitric Oxide(NO)generation,endothelia nitric oxide synthase(eNOS)plays an important role to maintain the balance of NO,which is a vasodilatation factor.Life for a long time in high altitude hypoxic regions of Tibetan chicken,formed a unique mechanism of hypoxia adaptation.In this paper,the structure of eNOSgene,coding product features and functions were reviewed,meanwhile,eNOSgene of Tibetan chicken involved in genetic mechanism of hypoxia adaptation are discussed,in order to provide help for the researches of origin,evolution,breeding of poultry,etc.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
2015年第2期192-195,共4页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
关键词
藏鸡
低氧适应
NO
ENOS
Tibetan chicken
hypoxic adaptation
NO
eNOS
