人工真皮填充结合负压引流修复老年皮肤恶性肿瘤术后深度创面

Reconstruction of deep wounds in old patients with cutaneous malignant tumor after artificial dermis combined with negative pressure wound therapy

目的:探讨人工真皮填充结合负压引流修复老年皮肤恶性肿瘤术后深度创面组织缺损的临床效果。方法:2009年7月至2014年2月对34例老年皮肤恶性肿瘤患者行病灶扩大切除(部分加行区域淋巴结清扫)术,并用人工真皮填充封闭深度创面后负压引流12~16 d,然后行大张自体皮片移植等治疗,总结患者创面的修复和并发症发生情况。结果:34例患者经扩大切除病灶处理创面得到修复,无创面严重感染发生,修复后创面皮肤质量、外观良好。结论:人工真皮填充结合负压引流能有效解决皮肤恶性肿瘤扩大切除术后深部组织暴露等问题。

Objective: To evaluate the effects of artificial dermis combined with negative pressure wound therapy on repairing wound aft er resection of cutaneous malignant tumor in elderly. Methods: The clinical data of 34 hospitalized patients with cutaneous malignant tumor from July, 2009 to February, 2014 were retrospectively analyzed. The patients received local enlarged excision, artificial dermis covered wounds and 12–16 days of negative pressure wound therapy plus a free skin graft transplant on the surface with an artificial dermis. Recovery and complication aft er operation were assessed.Results: All wounds were restored successfully with good appearance. None severe infection happened.Conclusion: Artificial dermis combined with negative pressure wound therapy can repair wound effi ciently af ter cutaneous malignant tumor resection was performed for old patients.