摘要
海洋贻贝类生物通过足丝分泌的黏附蛋白,具有高强度、高韧性、防水性以及极强黏附性等特点,可以使其黏附在几乎所有基底材料上。大量研究表明,3,4-二羟基-L-苯基丙氨酸(多巴,DOPA)是海洋贻贝类生物分泌的相关黏附蛋白中的重要组成部分。而且,贻贝黏附蛋白所具有的这种超强黏附能力,主要与多巴中特有的分子结构以及其与基底材料的相互作用方式等相关。多巴胺作为多巴衍生物的重要成员,具有与多巴相似的结构和性质,同样可以实现对基材表面的黏附,因而引起了研究人员的极大关注。本文综述了多巴胺的结构、性质、聚合机理以及它们在材料学、仿生学、生物医学等不同领域的应用现状。
In nature,mussels secrete adhesive proteins with excellent properties of high strength,high toughness and water proofing,can attach to almost all types of substrate surfaces.Most of evidence has demonstrated that a large amount of 3,4-dihydroxyphenyalanine(DOPA)is in the adhesive proteins secreted by mussels,which is the main reason of the strong adhesion force.Dopamine as one kind of DOPA derivatives has the similar structure and properties with DOPA.Inspired by mussels,scientists have paid much more attentions on their research and application of dopamine.In this paper,the structure,properties and polymerization mechanism of dopamine were reviewed,and its application in different fields,such as materials,biomimetic and biomedicine science was also involved.
出处
《高分子材料科学与工程》
EI
CAS
CSCD
北大核心
2015年第1期185-190,共6页
Polymer Materials Science & Engineering
基金
国家自然科学基金青年科学基金资助项目(51203087)
中央高校基本科研业务费专项资金资助(GK201102003)
关键词
多巴胺
黏附性
表面修饰
生物矿化
应用
dopamine
adhesive property
surface modification
biomineralization
application
