手性除草剂异丙甲草胺毒理研究进展

Progress in toxicity of chiral herbicide metolachlor

异丙甲草胺是目前广泛使用的酰胺类芽前阔叶杂草防除剂。文章综述了异丙甲草胺进入环境后对非靶标生物急性毒性、慢性毒性的对映体选择性差异,这种选择性差异与生物体的吸收及代谢密切相关。最后对异丙甲草胺手性毒理的未来研究进行了展望。

Chiral herbicide metolachlor is widely used for preemergence control of broad-leaved weeds.This review focused on its enantioselective differences of acute and chronic toxicities to non-target organisms after entering the environment.These differences are closely related to biological absorption and metabolism.The developmental trends of future investigations on chiral toxicology were also discussed.