缺血性脑血管病患者颈动脉粥样硬化斑块不稳定性的临床研究

A clinical study on the instability of carotid plaques in ischemic cerebrovascular patients

目的探讨缺血性脑血管病人颈动脉粥样硬化斑块不稳定性与高血压、糖尿病等危险因素及部分炎症因子间的关系。方法将112例缺血性脑血管病病人按颈动脉超声表现分为三组:正常动脉型、稳定型颈动脉硬化组、不稳定性斑块组;比较三组病人高血压病史、糖尿病史存在率。同时也比较了三组病人的外周血白细胞计数及血浆纤维蛋白原值。结果 三组病人上述指标间的差异经统计学处理均有显著性。结论 高血压、糖尿病及部分炎症因子与颈动脉粥样硬化斑块的不稳定性有关。

Objective To explore the relations between hypertension, diabetes, some inflammatory factors and unstable plaques of carotid atherosclerosis in ischemic cerebrovascular patients.Methods 112 cases are divided into 3 groups according to their carotid ultrasonic examination: normal carotid artery, stable carotid atherosclerosis, unstable plaque; compare the proportion of their hypertension and diabetes histories. Compare the WBC and plasma Fg of the 3 groups. Results There are significant differences in the proportions of their hypertension,diabetes historys between the stable and unstable groups; there are significant differences in WBC and plasma Fg between the 3 groups. Conclusion There is a closed relationship between these risk factors, inflammatory factors and unstable plaques of carotid atherosclerosis in ischemic cerebrovascular diseases.