肺癌脑转移的MR表现与诊断

MR manifestations and diagnosis of b rain metastases of lung cancer

目的评价MRI对肺癌脑转移的诊断作用。方法回顾性分析45例经病理证实的肺癌脑转移的MR表现,所有病例均经平扫和增强扫描,增强造影剂(Gd-DTPA)用量40例为0.2mmol/kg;5例为0.1mmol/kg。结果肺癌脑转移可表现为单发或多发病灶,形态多为圆形或类圆形,灶周可有或无脑水肿。分布主要在幕上皮、髓质交界区,但幕下小脑半球出现的比例也不低。增强扫描不仅能发现平扫未能显示的病灶,且85%的病例发现了更多的病灶。结论MRI,特别是增强检查是诊断肺癌脑转移的好方法。

Objective To evaluate the MRI diagnosis of brain metastases of lung cancer.Methods MR findings of 45patients with brain me tastases of lung cancer confirmed by pathological examinations were stu died retrospectively.Both non-contrast and contrast-enhanced scans were p erformed in all cases,in which 0.2mmol /kg of Gd-DTPA was administrated in 40patients and 0.1mmol /kg in 5patients.Results The brain metastases of lung cancer were solitary or multipl e,and round or oval in shape.Peri-le sion brain edema may present or absen t.The location of metastases were main ly in supratentorial areas between t he cortex and white matter but also we re frequently seen in cerebella.Contr ast-enhanced imaging revealed not o nly the lesions silent in non-enhanced scan,but also shown more nodules in 85%of p atients.Conclusion MRI ,especially with contrast-enhanced imaging was a very good diagnostic modality f or detecting brain metastases of lung cancer.[