皮疾灵口服液质量标准研究

Study on Quality Standards for Pijiling Oral Liquid

目的 建立皮疾灵口服液质量标准。方法 采用TCL法对处方中金银花、板兰根进行鉴别;用HPLC法测定绿原酸的含量。结果 在TCL色谱中检出金银花、板兰根;绿原酸在0.0098～0.049mg·ml-1,范围内呈良好的线性关系,r=0.9995;平均回收率98.95%, RSD为0.3%。结论 所建立的方法简便可行,重现性好,为皮疾灵口服液质量控制提供了方法。

Objective To establish quality standards for pijiling oral liquid. Methods FlosLonicerae and Radix Isatidis were identified by TLC. Chlorogenic acid Was determined by HPLC.ResultsFlos Lonicerae and Radix lsatidis could be detected by TLC. Chlorogenic acid showed a good linearrelationship at arane of 0,0098～0.049mg .ml-1r=0.9995,The average recovery was 98.95%,and RSDwas 0.3%.Conclusions The established methods are simple,feasible and reprodacible. This studyprovided a method for the quality control of pijiling oral liquid.