摘要
目的 建立新疆维吾尔族 1 5个STR基因座的等位基因分布基础遗传数据库 ,并比较其与天津汉族群体调查结果的差异。方法 应用荧光标记复合扩增、ABI 31 0 0 (Avant)型基因分析仪检测新疆 2 6 5名无关个体AmpFeSTR○RIdentifilerTM系统 ,统计 1 5个STR基因座的群体遗传参数。结果 2 6 5名无关个体 1 5个STR基因座中共检出 1 5 7个等位基因及 5 2 3种基因型 ,累计个体识别力 (TDP)为 0 999999999999999998,累积非父排除能力 (PE)为 0 .99999984 (三联体 )。结论 新疆维族 1 5个STR基因座的等位基因呈高度多态性分布 ,与天津汉族群体调查数据无显著差异 。
Objective To build basic heredity database of the distribution of allele frequencies and haplotype of 15 STR loci of Uygur population in Xinjiang, and to compare results of data with Han population in Tianjin. Method By using AmpFeSTR~ ~ ○R Identifiler~ (TM) Kit,265 unrelated individuals of the Uygur population in Xinjiang, were analyzed by ABI-3100(Avant)genetic analyzer,and the data of 15 STR loci were studied statistically. Results In the Uygur population(265 unrelated individuals) in Xinjiang, 157 alleles and 523 genotypes of 15 STR loci were found, TDP Was 0 999999999999999998, and PE Was 0 99999984(triple). Conclusion The distribution of alleles of 15 STR loci of the Uygur population in Xinjiang showed haplotype,no noticeable difference, and are suitable for forensic indentification and paternity testing.
出处
《刑事技术》
2004年第3期14-17,共4页
Forensic Science and Technology
基金
天津市公安科技基金资助研究课题 (津 2 0 0 30 85 1 )
