双水平气道正压通气治疗急性左心衰血流动力学与临床疗效的相关研究

Clinical study of BiPAP in the treatment of acute left ventricular failure

目的 研究双水平气道正压通气治疗急性左心衰竭时血流动力学效应与临床疗效的关系。方法 将 37例急性左心衰竭病人随机分为两组。对照组采用常规药物治疗加面罩吸氧 ;治疗组采用常规药物治疗加双水平气道正压通气。分别观察临床表现、动脉血气及血流动力学变化情况。结果 治疗组能更迅速更显著地改善临床症状、动脉血气及血流动力学。血流动力学效应与临床症状及动脉血气的改善同步。结论 双水平气道正压通气改善了急性左心衰竭的血流动力学 ,它使急性左心衰过度升高的左心室前负荷迅速下调至合适水平可能是其治疗急性左心衰竭的重要机制之一。

Objective To study the relation between hemodynomic effects and clinical efficacy of BiPAP on acute left ventricular failure.Methods 37 patients with acute left ventricular failure were randomly divided into two groups:control group(treated with ordinary drugs) and treatment group(treated with ordinary drugs and BiPAP).The changes of clinical symptoms,arterial blood gas and hemodynamic effect were measured to evaluate the efficacy of BiPAP ventilation.Results The clinical symptoms,arterial blood gas and hemodynamic effect of treatment group were all improved significantly and quickly.The improvement of clinical symptoms,arterial blood gas and hemodynamic effect was synchronic.Conclusion BiPAP could improve hemodynamics in patient with acute left ventricular failure.It helps in offsetting excussive preload of left ventricle,which may be an important mechanism in the treatment of acute left ventricular failure.