良性前列腺增生治疗药物对前列腺细胞增殖与凋亡的影响
Effect of therapeutic drugs for benign prostatic hyperplasia on proliferation and apoptosis of prostatic cells
摘要
前列腺细胞的增殖和凋亡受多种因素调节 ,细胞增殖率上调和细胞凋亡率下调是良性前列腺增生的重要原因。此文简要介绍良性前列腺增生治疗药物的一般作用机制 。
出处
《中国生化药物杂志》
CAS
CSCD
2004年第3期184-186,共3页
Chinese Journal of Biochemical Pharmaceutics
参考文献18
-
1David LH, Adam TG, Patricia F, et al. Epithelial Cell Differentiation Pathways in the Human Prostate: Identification of Intermediate Phenotypes by Keratin Expression[J]. J Histochem Cytochem, 2001,49(2): 271-278.
-
2Kyprianou N, Jacobs SC. Induction of apoptosis in the prostate by alphal-adrenoceptor antagonists: a novel effect of "old" drugs [J]. Curr Urol Rep, 2000, 1(2):89-96.
-
3Boesch ST, Dobler G, Ramoner R, et al. Effects of α1-adrenoceptor antagonists on culture prostatic smooth muscle cells[J]. Prostate,2000,45(4):34-39.
-
4Kirby RS, Roehrborn C, Boyle P, et al. Efficacy and tolerability of doxazosin and finastefide, alone or in combination, in treatment of symptomatic benign prostatic hyperplasia: the prospective european doxazosin and combination therapy (PREDICT) trial[J]. Urol, 2003,61(1):119-126.
-
5Cuellar DC, Rhee J, Kyprianou N. Alphal-adrenoceptor antagonists radiosensitize prostate cancer cells via apoptosis induction[J]. Anticancer Res,2002,22(3):1673-1679.
-
6Murakoshi M, Ikeda R, Fukui N, et al. Relationship between prostatic atrophy and apoptosis in the canine spontaneous benign prostatic hyperplasia (BPH) following chlormadianne acetate (CMA) [J]. Tokai J Exp Clin Med, 2001,26(2):71-75.
-
7Falkman J. Is tissue mass regulated by vascular endothelial cell: prostate as the first evidence[J]. Endocrinol, 1998,139(11):441-444.
-
8Coffey DS. Controversies in the management of lower urinary tract symptoms: an overview[J]. Brit J Urol, 1998,81(Suppl 1):1-5.
-
9Wu SF, Sun HZ, Qi XD, et al. Effect of epristeride on the expression of IGF-1and TGF-β receptors in androgen-induced castrated rat prostate[J].Exp Biol Med, 2001,226(10):954-960.
-
10Roehrborn CG, Boyle P, Nickel JC, et al. Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2(dutasteride) in men with benign prostatic hyperplasia [J]. Urol, 2002,60(3) :434-441.
-
1汤平,谢克基.α_1-肾上腺素能受体阻滞剂与前列腺细胞凋亡[J].广东医学,2002,23(7):765-767.
-
2朱建林,陈昱,刘瑾,杨华,吴传城,李昱辰,陈锦,任南.壬基酚对大鼠前列腺细胞凋亡影响及机制[J].中国公共卫生,2013,29(8):1187-1189.
-
3谢立平,秦杰.特拉唑嗪与前列腺细胞凋亡[J].中华医学信息导报,2004,19(16):16-16.
-
4许长江,李端,陆洪芬.氟他胺与2-羟基氟他胺诱导正常大鼠前列腺细胞凋亡[J].中国药理学通报,2000,16(3):290-292. 被引量:1
-
5王志平,陈一戎,刘国栋.花粉提取物对前列腺增生细胞作用的研究[J].中华泌尿外科杂志,1995,16(12):732-733. 被引量:15
-
6钱立晖,王晓麟,屠曾宏.Inhibition of regrowth of prostatic glandular cells by epristeride[J].Acta Pharmacologica Sinica,2001,22(9):847-850.
-
7各科药物[J].国外科技资料目录(医药卫生),1998(3):188-189.
-
8江振洲,束文慧,张陆勇,严明,孙立,王广基.爱普列特对良性前列腺增生体外细胞模型的凋亡诱导作用[J].中国临床药理学与治疗学,2006,11(6):644-649. 被引量:2
-
9刘本臣.中医药治疗良性前列腺增生症的研究进展[J].中国实用医药,2007,2(34):144-146. 被引量:3
-
10申旭波,周远忠,姜慧,周希雷,贾菲菲,熊云刚,邹焰.低剂量砷长期诱导人肝细胞获得耐砷性的实验研究[J].现代医药卫生,2009,25(17):2577-2579. 被引量:1