金钗石斛化学成分的研究

Studies on the chemical constituents of Dendrobium nobile

目的 对金钗石斛 (DendrobiumnobileLindl )茎的化学成分进行研究。方法 使用硅胶柱色谱进行分离纯化 ,理化性质和光谱分析鉴定结构。结果 分离并鉴定了 5个单体化合物及 2个系列混合物。分别为海松二烯 ,3 甲氧基 4 羟基反式肉桂酸二十二烷酯 ,3 甲氧基 4 羟基反式肉桂酸二十四烷酯 ,豆甾醇 ,对羟基顺式肉桂酸三十烷酯 ,对羟基反式肉桂酸直链烷酯的4个系列化合物的混合物 ,直链烷醇的 5个系列化合物的混合物。结论 以上成分均为首次从该种植物中分得 ,其中海松二烯为首次从该属植物中分得。

OBJECTIVE: To study the chemical constituents of Dendrobium nobile Lindl. METHODS: The constituentes were isolated through column chromatography and identified on the basis of their physiochemical and spectral data. RESULTS: Five monomers and two mixtures were isolated and identified as pimaradiene, n-docosyl ferulate, n-tetracosyl ferulate, stigmasterol, n-triacontyl cis-p-coumarate, the mixture of n-tetracosyl trans-p- coumarate, n- hexacosyl trans-p-coumarate, n-octacosyl trans-p-coumarate and defuscin, respectively, and the mixture of n-hexacosyl alcohol and n-octacosyl alcohol and n-triacontyl alcohol, n-hentriacontyl alcohol, n-dotriacontyl alcohol. CONCLUSION: All these constituentes were isolated from this plant for the first time. Pimaradiene was isolated from Dendrobium genus for the first time.