以复方铋剂为主的四联疗法根除幽门螺杆菌的药物经济学评价

Evaluation of Pharmacoeconomics of Quadruple Drug Therapy with Complex Bismuth Agent as the Main Drug for Eradicating Helicobater Pylori

目的 :探讨不同药物治疗方案对同一疾病所产生的经济效果。方法 :根据文献选择Hp阳性感染患者 734例 ,随机分为 6组 ,分别给予不同的药物治疗方案 ,运用药物经济学的成本 -效果分析方法进行分析评价。结果 :6种药物治疗方案总成本依次为 10 19 32元、14 94 34元、818 98元、10 93 6 6元、789 30元、10 34 30元 ,Hp的根除率依次为 85 4 4 %、93 75 %、88 35 %、86 5 2 %、82 35 %、87 94 %。结论 :B1 组为最佳药物治疗方案。

OBJECTIVE:To study economic effect of different drug treatment projects on the same disease .METHODS: 734 patients with Hp positive infection were divided into 6 groups. They were treated with different drug treatment projects,and analyzed and evaluated by cost-effectiveness analysis of pharmacoeconomics.RESULTS: The total costs of these 6 kinds of drug treatment projects were 1 019.32 yuan,1 494.34 yuan,818.98 yuan,1 093.66 yuan, 789.30 yuan and 1 034.30 yuan. Eradication rate of Hp was 85.44%,93.75%,88.35%,86.52%, 82.35% and 87.94%, respectively. CONCLUSION: Group B 1 is considered to be the best drug treatment project.