甲亢、甲低患者血清生长抑素含量及分析

Measurement of Serum Somatostatin (SS) Levels in Hyperthyroid and Hypothyroid Patients

目的 :探讨甲亢、甲低患者血清SS与正常人含量的关系及临床意义。方法 :应用放射免疫分析检测39例甲亢 ,39例甲低及 4 2例正常人血清SS含量。结果 :甲亢患者血清SS含量明显高于正常对照组 ,甲低患者SS含量明显低于正常对照组。经统计学分析 ,甲亢、甲低组与正常组对比具有显著性差异 (P <0 0 5 )。结论 :甲亢患者SS含量高于对照组 ,甲低患者SS含量低于对照组。血清中SS与甲状腺激素水平有一致性改变。

Objective To investigate the clinical significance of changes of serum somatostatin (SS) levels in patients with different thyroid function state. Methods Serum SS levels were measured with RIA in 39 hyperthyroid subjects, 39 hypothyroid subjects and 42 controls. Results Serum SS levels were significantly higher in hyperthyroid patients and significantly lower in hypothyroid patients than those in the controls (both P<0.05). Conclusion Serum SS levels vary parallelly to serum thyroid hormone levels.