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免疫抑制药物抑制树突状细胞分化与功能研究进展 被引量:2

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摘要 免疫抑制药物多应用于防治移植排斥、移植物抗宿主病或宿主抗移植物病、超敏反应引起的疾病和自身免疫性疾病 ,其作用机制的研究以往多偏重于对T、B细胞的影响。随着DC(dendriticcell,DC)功能研究的深入 ,免疫抑制药物作用于DC的研究结果完善了免疫抑制性药物调节免疫应答的作用机制。
出处 《国外医学(免疫学分册)》 2004年第4期209-214,共6页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
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  • 1Penna G,Adorini L.1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation,maturation,activation,and survival of dendritic cells leading to impaired alloreactive Tcell activation[J].J Imnunol,2000,164(5) :2405-2411.
  • 2Matsue H, Yang C, Matsue K, et al.Contrasting impacts of immunosuppressive agents ( rapamycin, FK506, cyelosporin A, and dexamethasone)on bidirectional dendritic cell-T cell interaction during antigen presentation[J] .J Immunol,2002,169(7) :3555-3564.
  • 3Sehgal SN.Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression [ J ].Clin Biochem, 1998,31 ( 5 ): 335-340.
  • 4Qiu D,Zhao G, Aoki Y,et al.lmmnunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation[ J ].J Biol Chem.1999 ;274(19): 13443-13450.
  • 5Xing N, L Maldonado ML, Bachman LA, et al.Distinctive dendritic cell modulation by vitamin D ( 3 ) and glucocorticoid pathways [ J ].Biochem Biophys Res Commun,2002,297(3) :645-652.
  • 6Zhao G, Vaszar LT, Qiu D, et al.Anti-inflammatory effects of triptolide inhuman bronchial epithelial cells[ J].Am J Physiol Lung Cell Mol Physiol,2000,279(5): L958-966.
  • 7Hackstein H,Taner T, Logar AJ, et al.Rapamycin inhibits macroropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells[J].Blood,2002,100(3): 1084-1087.
  • 8Lee KY, Chang W, Qiu D,et al.PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells[ J].J Biol Chem, 1999,274(19): 13451-13455.
  • 9Hackstein H, Morelli AE, Larregina AT, et al.Aspirin inhibits in vitro maturation and in vivo immunostimulatory function of murine myeloid dendritic ce11s[J] .J Immunol,2001,166(12) :7053-7062.
  • 10Caldwe11 S, Heitger A,Shen W, et al.Mechanisms of genglioside inhibition of APC function[J] .J Immunol,2003,171(4): 1676-1683.

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