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抑癌基因ING1在胃癌组织中的表达及其意义

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摘要 目的 探索ING1在胃癌组织中的表达及其意义。方法 采用免疫组化法检测51例胃癌组织及15例正常胃粘膜中p33^ING1b的表达情况。结果 p33^ING1b在胃癌组织中的表达率为41.2%(21/51)。远低于在正常胃粘膜中的表达率100%(15/15)。结论 ING1是抑癌基因,其蛋白产物p33^ING1b在胃癌组织中低表达,对胃癌的发生、发展可能起重要作用。
出处 《美国中华临床医学杂志》 2004年第2期127-129,共3页 American Journal of Chinese Clinical Medicine
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