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细胞生长因子治疗爆震性鼓膜穿孔24例临床观察

Treatment of Blast Tympanic Membrane Perforation with Cell Growth Factor: A Clinical Study of 24 Cases
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摘要 目的:探讨bFGF贴片法治疗外伤性鼓膜穿孔的效果.方法:外伤性鼓膜穿孔24耳,经消炎急性炎症期后行bFGF鼓膜贴片,每天耳道内滴l滴~2滴环丙沙星,保持贴片湿润,6天~7天换bFGF贴片.结果:穿孔<5mml8耳经1次贴片全部愈合,穿孔>5mm6耳经4.3次贴片全部愈合,听力提高16dB.结论:bFGF贴片治疗外伤性鼓膜穿孔安全、简单、经济. Objective: To evaluate the roles of basic fibroblast growth factor (bFGF) in trauma tympanic membrane perforation. Methods: 24 cases of trauma tympanic membrane perforations were treated with bFGF path after acute inflammation period. Every day one or two drops of antibiotic after 6-7days, the patch of bFGF were gotten out. Results: Eighteen ears with perforation <5mm were all cured by mean 1.7 times with bFGF. The six ears with perforation≥5mm were cured by mean 4.3 times with bFGF. Hearing increase 16dB. Conclusion: bFGF, It was a good method to treat trauma tympanic membrane perforation with bFGF and it was a safe .simple cheap method.
出处 《伤残医学杂志》 2004年第2期36-37,共2页 Medical Journal of Trauma and Disability
关键词 细胞生长因子 爆震性鼓膜穿孔 外伤性 中耳炎 Tympanic membrane perforation Trauma bFGF
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参考文献4

  • 1Goeverts PJ.Jacob Wa,Marquet J.Histologeal study of the thin replcement membrane of pertoratim[J].Acta Oaolaryngol,1998,105:297-302.
  • 2Griffn WL.A retrospective study of traumatic tyavpanic membrane perforation in a clinical practive[J].Laryngosope,1979,89:81-82
  • 3Mcintire C.Spontaneous repair of the tympanic membrane: Histological studies in the cat[J].Ann Otol Rhinol laryngol,1970,79:1129-1131.
  • 4Laidlow DW,costantion PD,Govindaraj S,ctal,Tympamic membrane repair with a dermal allagrft[J].Larynoscope,2001,111:702-707.

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