刺五加注射液对小鼠急性心肌缺氧的保护作用

Protective effect of Acanthopanecis senticosus injection in rats with acute myocardial hypoxia

目的 :观察刺五加对小鼠急性心肌缺氧的保护作用。方法 :常压和低压缺氧条件下分别观察小鼠平均存活时间和心肌耗氧量。结果 :刺五加注射液高低剂量组均可使小鼠常压和低压条件下平均存活时间延长 ;降低常压、低压条件下心肌耗氧量。结论 :刺五加注射液能明显降低小鼠心肌氧耗 ,提高小鼠抗应激能力 。

AIM: To observe the protective effect of Acanthopanecis senticosus injection in rats with acute myocardial hypoxia. METHODS: The mean survival time and capacity for myocardial oxygen consumption were detected in rats with acute hypoxia under ordinary or low pressure. RESULTS: Various dosages of Acanthopanecis senticosus injection could prolong the mean survival time and reduce capacity for myocardial oxygen consumption in rats with acute hypoxia under ordinary or low pressure. CONCLUSION: The Acanthopanecis senticosus injection can evidently reduce capacity for myocardial oxygen consumption and increase ability to anti-stress and plays a protective role in rats with hypoxic myocardium.