踏车运动试验评价异搏定与地戈辛治疗房颤的临床疗效

Appraising the clinical effect of digoxin or/and verapamil therapy by ergometry bicycle exercise test on patients with airial fibrillation

术文通过踏车运动试验对28例风心病房颤患者应用地戈辛(D)和异搏定(V)治疗进行观察,结果显示:单用 V 和 D+V 两种治疗在控制房颤静息和运动状态下心室率、提高运动耐受力均优于单用 D 治疗。临床观察认为,对于心功能Ⅰ～Ⅱ级者就减低房颤心室率而言,异搏定可取代地戈辛作为首选治疗,但对既往有心衰史、心功能差者,两药合用更为安全有效。

28 patients suffering from rheumatic heart disease with atrial fibrillation on digoxin or/and verapamil therapy were studied by exgomey bicycle exercise test.Results were as follow:verapamil alone and verapamil plus digoxin were superior to digoxin in controlling resting and exercising ventricular rate and improving exercise capacity in patients with atrial fibrillation.The results suggested that verapami is the treatment of first choice in educing ventricular rate of patients with atrial fibrillation,whose cardiac function is Ⅰ-Ⅱ degree.If the patients cardiac function was worse,combining use of digoxin and verapamil is more safe and effect.