生物序列比对算法的实现与集成

Develop and integrate the algorithms of biological sequence alignment

为了使不同的比对算法产生的结果能够方便地横向比较进而评价最佳的比对模式,深入地研究了序列比对领域最经典和最常用的比对算法,其中包括经典的动态规划、半经验式的 BLAST 和 FASTA、启发式的 CLUSTALW 以及相似组方法等,并对各种方法加以程序化的实现,研制成功了集成化的序列比对平台,为科研人员提供了有效的序列比对及其评价工具。

Studied the most classical and normal alignment in the field of sequence alignment and made it available in our software de-sign.We have been built an integrated sequence alignment system to make it easier of comparison in different algorithms,such as dy-namic programming algorithm,BLAST,FASTA,CLUSTALW,similar group algorithm,and given a better pattern of alignment.Thissystem will afford an efficient tool of sequence alignment for the researchers.