摘要
本研究以与氧自由基损伤有关的生化指标:血浆肌酸磷酸激酶(CPK),心肌组织脂质过氧化物(LPO)和硒谷胱甘肽过氧化物酶(SeGSHPx)以及心肌功能指标:左心室峰压(LVSP).左心室舒张末压(LVEDP)和心室内压最大上升,下降速率(±dp/dt max)。说明生脉散对在体心肌缺血再灌流损伤有明显的保护作用,其效果与SOD相当。
In the present study,by the biochemical indexes related to oxygen free radical damage:the levels of plasma creatine phosphokinase,tissue lipoperoxide and selenium glutathione peroxidase,and the indexes of cardial contractile function:LVSP, LVEDP and ±dp/dt max,a significant protective effect of Chinese recipe Sheng Mai San on ischemic reperfused myocardium was shown. The protective efficiency of sheng Mai San was egual to that of antioxidative enzyme superoxide dismutase to some extent.
出处
《第一军医大学学报》
CSCD
1993年第1期43-46,共4页
Journal of First Military Medical University
基金
国家自然科学基金资助项目
关键词
脂质过氧化
生脉散
超氧物歧化酶
Creatine phosphok inase
lipoperoxide
Selenium glutathione peroxidase
cardial contractile function
Sheng Mai San
Superoxide dismutase
ischemic reperfusion
