婴幼儿暴发型流行性脑脊髓膜炎的胸腺病理变化

Pathologic Changes of Thymus in Fulminating Meningitis of Infants

观察10年间13例婴幼儿暴发型流行性脑脊髓膜炎的胸腺主要病理变化,见胸腺增大,重量增加;淋巴细胞消减;不规则核型淋巴细胞增多;胸腺抚育细胞的反应性增生以及胸腺小体增生、变性、钙化。首次报道了常规制片、HE染色的病理切片中胸腺抚育细胞的分布、形态、大小。

The major pathologic changes of the thymus were reported in 13cases of infantile meningitis observed in 10 years period. The changeswere increases in the size & weight of the thymus. The lymphocyteswere decreased in number & lymphocytes with irregular nuclear patternwere increased. The thymic nurse cells showed reactive proliferation.The thymic corpulscles showed proliferation, degeneration & calcification. In this paper we also report for the first time the distribution,morphology & size of the thymic nurse cells in routinely prepared H.E. staining sections.