前列腺增生症之膀胱逼尿肌改变的临床研究

Detrusor dysfunction in patients with benign prostatic hyperplasia

目的 探讨前列腺增生症的膀胱逼尿肌改变。方法 对 30 0例前列腺增生症患者进行尿动力学检查分析 ,包括充盈性膀胱测压、压力 流率同步检查。结果 30 0例检测结果 :最大逼尿肌压力 (Pdet) 0～ 14 9cmH2 O ,平均 (5 9 2 4± 37 87)cmH2 O ,BC值平均 (2 5 6± 4 93)ml cmH2 O ,逼尿肌不稳定 (DI) 5 2例 (17 33% ) ,逼尿肌无力 36例 (12 % )。本组BC值 <30者 132例 ,即低顺应性膀胱 132例 ;BC值 >4 0者 83例 ,即高顺应性膀胱 83例。DI和低顺应性与BOO相关 (P <0 0 5 )。结论 尿动力学检查有助于了解前列腺增生症患者的膀胱逼尿肌功能改变 ,明确患者排尿困难的原因 ,指导诊断和选择治疗方法 ,预测预后和判断疗效。DI和低顺应性与BOO相关。

Objective To study the detrusor dysfunction in patients with benign prostatic hyperplasia.Methods Urodynamic data of 300 patients with benign prostatic hyperplasia was analyzed.Results The mean detrusor pressure was (59.24±37.87) cmH 2O,the mean bladder compliance (BC) was (25.6±4.93) ml/cm H 2O,the BC in 132 patients was smaller than 30,and in 83 patients bigger than 40.There were 52 patients with detrusor instability,and 36 patients with detrusor underactivity.There was correlation between DI or BOO and BOO (P<0.05).Conclusion Urodynamic examination reveals detrusor dysfunction in patients with benign prostatic hyperplasia,and it can determine the cause of difficulty in voiding,and is important in the diagnosis and the selection of the treatment for the patients.