改良超滤对婴幼儿心脏手术输血的影响

The effect of modified ultrafiltration on blood transfusion in infants undergoing cardiac surgery

目的 观察改良超滤技术在婴幼儿体外循环心血管手术中对输血及术后出血的影响。方法 6 0例接受体外循环下心血管手术的先天性心脏病患儿 ,均分为对照组 (不接受任何超滤 )、常规超滤组 (CUF组 )和改良超滤组 (MUF组 )。观察术中库血用量、血浆用量、血球压积的变化及术后2 4h出血量 ,并用SSPS/PC进行统计学处理。结果 MUF组库血用量、血浆用量、术后 2 4h出血量显著低于对照组和CUF组 (P <0 0 1) ,且滤出水量明显多于CUF组 (P <0 0 1)。结论 在婴幼儿心血管手术中 ,改良超滤可有效排出体内水分 ,提高血球压积 ,明显减少输血及术后出血 ,是节约用血的重要手段之一。

Objective To study the effect of modified ultrafiltration (MUF) technique on transfusion and postoperative bleeding in infants undergoing cardiovascular operation under cardiopulmonary bypass .Methods 60 infants accepted cardiovascular operation were equally divided into three groups : control group,conventional ultrafiltration group (CUF,n=20) and modified ultrafiltration group (MUF).The requirements of bank blood and fresh frozen plasma (FFP), the change of heamatocrit (Hct) and the volume of chest drainage within 24 hours postoperative were recorded. Results Compared with the control and CUF groups, the volumeof blood transfusion, FFP and the postoperative drainage in group MUF were significantly less(P<0.01). Conclusion MUF technique could get some body water out ,elevate Hct and decrease blood transfusion and postoperative blood loss in theinfants undergoing cardiovascular surgery.