PET发射和透射扫描三维图像融合显示技术的建立

The establishment of the method of three dimension volumetric fusion of emission and transmission images for PET imaging

目的 建立可在PC机上运行的PET显像发射和透射扫描三维图像融合显示技术。方法 将SiemensECATHR+ 型PET仪1 8F 脱氧葡萄糖 (FDG)PET全身显像发射扫描和透射扫描原始三维图像容积数据 ,经数据转换、图像转换、三维几何和观察变换、图像融合等实现PET发射和透射扫描三维图像融合 ,图像融合采用Alpha通道方式。通过临床应用验证融合图像的定位准确性。结果PET发射和透射扫描三维立体融合图像可清晰显示胸部体表轮廓、双肺野、胸壁、纵隔、心脏等解剖结构 ,可在PC机上运行。 13例患者位于胸壁、胸膜、肺组织、纵隔的 4 8个病灶在PET胸部发射和透射扫描三维融合图像上均正确定位 ,与CT、MRI、全身骨显像等定位结果一致。结论 SiemensECATHR+ 型PET仪发射和透射扫描图像三维容积数据坐标轴一致 ,胸部发射和透射扫描三维图像融合对胸壁、纵隔等部位病灶与肺内病灶的鉴别诊断有一定价值。

Objective To establish the method of three dimension volumetric fusion of emission and transmission images for PET imaging. Methods The volume data of emission and transmission images acquired with Siemens ECAT HR + PET scanner were transfered to PC computer by local area network. The PET volume data were converted into 8 bit byte type, and scaled to the range of 0～255. The data coordinates of emission and transmission images were normalized by three-dimensional coordinate conversion in the same way. The images were fused with the mode of alpha-blending. The accuracy of image fusion was confirmed by its clinical application in 13 cases. Results The three dimension volumetric fusion of emission and transmission images clearly displayed the silhouette and anatomic configuration in chest, including chest wall, lung, heart, mediastinum, et al. Forty-eight lesions in chest in 13 cases were accurately located by the image fusion. Conclusions The volume data of emission and transmission images acquired with Siemens ECAT HR + PET scanner have the same data coordinate. The three dimension fusion software can conveniently used for the three dimension volumetric fusion of emission and transmission images, and also can correctly locate the lesions in chest.