炎症型恶性纤维组织细胞瘤

Inflammatory Malignant Fibrous Histiocytoma

目的:探讨炎症型恶性纤维组织细胞瘤的临床病理特点以及治疗、预后。方法:分析3例炎症型恶性纤维组织细胞瘤病例,并结合国外文献资料进行分析。结果:发热、白细胞计数显著升高等类白血病样表现及肿块为炎症型恶性纤维组织细胞瘤的常见症状。手术是有效的治疗方法,化疗效果差。结论:炎症型恶性纤维组织细胞瘤是极罕见的高度恶性软组织肉瘤,早发现、早治疗是提高其治愈率、延长生存时间的关键。

Objectives: To investigate clinical and pathological features of Inflammatory Malignant Fibrous Histiocytoma and its treatment as well as prognosis. Methods: Analyze the three cases of Inflammatory Malignant Fibrous Histiocytoma in our department and literatures from foreign journals. Resaults: Inflammatory Malignant Fibrous Histiocytoma always presents leukemoid reaction symptoms such as fever, WBC counts elevation and mass with poor prognosis. Immunohistochemical examination can improve differentiation of diagnosis. Surgery is an effective treatment while chemotherapy has no remarkable response. Conclusions: Inflammatory Malignant Fibrous Histiocytoma is very rare but a high grade tumor. Early detection and early treatment play the key role in increasing its curability and elongating the patients' survival rate.