重比重利多卡因用于腰椎麻醉的临床观察

Clinical investigation of spinal anesthesia with hyperbaric lidocaine

目的 观察重比重利多卡因用于腰椎麻醉的临床效果和安全性。方法 随机选择 ASA - 级拟行外科手术的患者 1 0 0例 ,选择 L2 ～ L3或 L3～ L4 做腰麻穿刺点 ,局麻药液为 5 %重比重利多卡因 1 0 0 mg,观察并记录感觉神经阻滞效果 ,运动神经阻滞程度 (改良 Bromage评分 ) ,血压、脉搏、血氧饱和度的下降程度及副作用的发生情况。结果 除 5例因年龄较大合并心血管系统的疾病 ,给药后 5 min血压下降明显 (MAP<70 mm Hg) ,心动过缓 (HR<6 0 mm Hg) ,其余所有患者麻醉效果良好 ,恶心、呕吐、头疼的发生率低 (P<0 .0 1 ) ,呼吸循环系统功能稳定。结论 蛛网膜下腔给予 5 %重比重利多卡因 ,起效迅速、用药量少、阻滞完善、肌肉松弛且并发症少 。

Objective To investigate the clinical effect and safety of spinal anesthesia with hyperbaric lidocaine in Yemeni patients.Methods One hundred Yemeni patients scheduled for surgical operation were randomly selected.Puncture was located at L 2～3 or L 3～4 and 5% hyperbaric lidocaine was employed.Block effect and the level of anesthesia were assessed.Blood pressure,heart rate and side effects were recorded.Results Spinal anesthesia provides perfect and satisfactory effect without obvious nausea and vomiting or headache except five old aged patients suffering from heart disease.Respiratory and cardiovascular systems are stable.Conclusion Spinal anesthesia with 5% hyperbaric lidocaine has the advantage of faster onset of block,better anesthesia,more intense motor block and less local anesthesia.