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高血压病的基因治疗进展 被引量:3

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机构地区 广西民族医院
出处 《医学综述》 2004年第7期414-416,共3页 Medical Recapitulate
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参考文献22

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  • 4Phillips MI, Wielbo D, Gyurko R. Antisense inhibition of hypertension anew strategy for renin-angiotensin candidate genes [J]. Kidney Int,1994,46(6) : 1554-1556.
  • 5Ambuhl P, Gyurko R, Phillips MI. A decrease in angiotensin receptor binding in rat brain nuclei by antisense oligonucleotides to the anglotensin AT1 receptor[J]. Regul Pept, 1995,59(2) : 171-182.
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  • 7Wang H, Reaves PY, Gardon ML, et ol. Angiotensin l-converting enzyme antisense gene therapy causes permanent antihypertensive effects in the SHR [J]. Hvoertension, 2000,35 ( 1 ) : 202-208.
  • 8Phillips MI, Mohuezy-Dominiak D, Coffey M, et al. Prolonged reduction of high blood pressure with an in vivo, nonpathogenic, adeno-associated viral vector delivery of AT1 R mRNA antisense[ J]. Hypertension, 1997,29( 1 Pt 2) :374-380.
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  • 10Li P, Morris M. Diz DI, et al, Role of paraventricular angiotensin AT1 receptors in salt sensitive hypertension in mRen-2 transgenic rats[J].Am J Physiol, 1996,270(5 Pt 2) : 1178-1181.

二级参考文献57

  • 1[1]Phillips MI. Antisense inhibition and adeno-associated viral vector deliverv for reducing hypertension[J]. Hypertension,1997,29:177-187
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  • 3[3]Phillips MI. Is gene therapy for hypertensiou possible[ J ]. Hvpertension1999,33:8-13.
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  • 7[7]Wahletredt C. Antisense oligonucleotide strategies in neuropharmacology[J]. Trends Pharmacol Sci,1994,15:42-46.
  • 8[8]Campbell JM,Bacon TA,Wickstrom E. Oligodeoxynucleotide phosphoroth ioate stability in cubcellular extracts, culture media, ser and cerebrpspinal fluid[J ]. J Biochem Biophys Methods, 1990,20: 259-267.
  • 9[9]Loke SL,Stein CA,Zhang XH,et al. Characterization of oligonucleotidetransport into living cells[J]. Proc Natl Acad Sci USA, 1989,86: 3474-3478.
  • 10[10]Iversen PL,Mata L,Tracewell WG,et al. Pharmacokineties of an antisensephysphorothioate oligodeoxynucleotide against rev from human immuno de ficiency virus type 1 in adult male rat following single injections and contin uous infusion[J]. Antisense Res Dev, 1994.4: 43-52.

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