氟罗沙星治疗细菌性感染的药物经济学研究

Cost-effectiveness Analysis of Fleroxacin in Treatment of Bacterial Infections

目的评价氟罗沙星和氧氟沙星治疗细菌性感染的经济性。方法治疗组患者35例,使用氟罗沙星0.3g,静脉滴注,1次/d共10.5d;对照组患者32例,使用氧氟沙星0.3g,静脉滴注,2次/d,共10.5d。运用药物经济学的成本-效果分析方法进行评价。结果2种方案的成本-效果比(C/E)分别为22.87,20.43,效果(以有效率表示)分别为91%,84%(P>0.05)。结论氧氟沙星经济性最佳,氟罗沙星市场价格太贵,建议厂商重新考虑市场的药品定价策略。

Objective:To evaluate the cost-effectiveness of Fleroxacin and Ofloxacin in treatment of bacterial infections.Methods:Use cost-effectiveness analysis to evaluate 67 cases devided into A and B groups.A,received Fleroxacin 0.3 g,iv gtt,qd×10.5.B,received Ofloxacin 0.3 g,iv gtt qd×10.5.Results:The cost of A and B schemes were 22.87,20.43,respectively,and the effective ratio were 91%,84%(P > 0.05),respectively.Conclusion:B is the best scheme.The price of Fleroxacin is too expensive.The factory should better lower the price of Fleroxacin.