谷氨酰胺、甘氨酰谷氨酰胺对断奶仔猪生长及内分泌的影响

Effects of Glutamine and Glycyl-glutamine on Growth Performance and Endocrine Function of Weaned Piglets

为探讨谷氨酰胺、甘氨酰谷氨酰胺对断奶仔猪生长及内分泌的影响 ,选取 2 1日龄断奶仔猪 72头 (纯种长白仔猪 4 0头 ,纯种大白仔猪 32头 ) ,随机分成 4组。A组为对照组 ,饲喂基础日粮。B、C、D组为试验组 ,饲喂在基础日粮的基础上分别添加 0 .5 %谷氨酰胺、0 .2 5 %甘氨酰谷氨酰胺、0 .5 %甘氨酰谷氨酰胺的日粮 ,饲养期 2 1d。结果表明 ,添加 0 .5 %谷氨酰胺、0 .2 5 %甘氨酰谷氨酰胺能显著提高仔猪的平均日增重 ,改善饲料转化率 ,血液中FT3 、FT4和IGF Ⅰ 水平有提高趋势 ;添加 0 .5 %甘氨酰谷氨酰胺组在 4 2日龄时血清胰岛素水平显著提高 (P <0 .0 5 ) ;添加甘氨酰谷氨酰胺的 2个试验组血清中皮质醇水平显著降低 (P <0 .0 5 ) ;添加谷氨酰胺和甘氨酰谷氨酰胺均能降低仔猪腹泻率。提示断奶仔猪日粮中添加甘氨酰谷氨酰胺可调节内分泌活动 ,促进仔猪生长。

Forty Landrace and 32 Yorkshire purebred piglets weaned at the age of 21 days were selected and divided into 4 groups based on breed, weight and gender. Pigs in Group A (control) was fed the basal diet and pigs in Group B, C and D as three trial groups were fed the basal diet added 0.5% glutamine, 0.25% glycly-glutamine and 0.5% glycly-glutamine, respectively. The trial lasted 21 days to investigate the effect of glycyl-glutamine and glutamine on the growth performance and endocrine function of the weaned piglets. The results showed that daily gain was increased significantly (P<(0.05)), feed conversion ratio was improved and levels of free thiiodothyronine (FT_3), free thyroxine (FT_4) and insulin-like growth factor-Ⅰ (IGF-Ⅰ) in blood tended to be increased in Groups B and C, and level of insulin in blood was increased significantly (P<0.05) in Group D at the age of 42 days. Level of cortisol in blood was decreased significantly in Groups C and D. Addition of glutamine or glycyl-glutamine to the basal diet decreased the diarrhea occurrence ratio significantly(P<0.05). The results indicated that addition of glycyl-glutamine could regulate endocrine function and improve growth performance in piglets.