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Junk DNA的功能诠释 被引量:4

Annotation for The Functions of Junk DNA
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摘要 在庞大的基因组序列中数量占绝对优势的序列因为不编码蛋白质或RNA产物 ,一直被人们称为 junkDNA .事事讲究经济效率的生物在长期的进化中 ,应该不会让大量无功能的“垃圾”堆积在充满活力的生命细胞中 .近年来的研究已揭示junkDNA具有重要的功能 ,随着研究的深入 ,一定会发现越来越多的junkDNA决非垃圾 。 The prevailing sequences in the massive genome sequences, which do not code for proteins or RNAs, have been named junk DNA. It is unreasonable for organisms, in which there is the principle of maximum economy, to accumulate nonfunctional garbage in vital living cells during their long-term evolution. Recent researches have demonstrated that so-called junk DNA possesses important functions and it is believed that more and more junk DNA will be proved to be not garbage but the treasures of the genome.
出处 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 2004年第6期479-481,共3页 Progress In Biochemistry and Biophysics
关键词 无功能DNA 重复序列 保守的非基因序列 nonfunctional DNA repetitive sequences conserved non-genic sequences
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参考文献5

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同被引文献76

  • 1孙志强,J.E.Spetch,GeorgeGraef.连锁情况下自交群体遗传组成的一般表达及紧密连锁基因的选择[J].遗传,1993,15(4):28-32. 被引量:8
  • 2王丽丽,章平.microRNAs及其功能的研究进展[J].细胞生物学杂志,2006,28(5):646-650. 被引量:5
  • 3Dermitzakis ET, Reymond A, Antonarakis SE. Conserved non-genic sequences-an unexpected feature of mammalian genomes. Nature Review Genetics ,2005,6 : 151-157.
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  • 8Naoyuki U, Brad T, Kook HC, et al. Regulation of SHOOT MERIS- TEMLESS genes via an upstream-conserved noneoding sequence co- ordinates leaf development. Proceedings of the National Academy of Sciences USA,2007,104 : 15953-15958.
  • 9Thomas B, Dietmar Q, Marcus K. Molecular evolution and phylngenetic utility of non-cnding DNA : applications from species to deep level questions. Plant Systematic Evolution ,2009,2 : 108-110.
  • 10Zhang L, Kasif S, Cantor CR, et al. GC/AT-content spikes as genomic punctuation marks. Proceedings of the National Academy of Sciences USA ,2004,101 : 16855-16860.

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